Anterior subcapsular lens deposits are associated with which drug?

• A. Amiodarone
• B. Digoxin
• C. Warfarin
• D. Clonidine

Answer: (A)

Anterior subcapsular lens deposits are a recognized ocular finding linked to certain systemic medications, notably amiodarone. Amiodarone is highly lipophilic and can accumulate in ocular tissues over time, leading to deposits in the anterior portion of the lens as well as corneal changes. These deposits are part of amiodarone’s spectrum of ocular toxicities and correlate with long-term use.

Other drugs listed have different eye effects and are not typically associated with anterior subcapsular lens deposits. Digoxin is known more for visual disturbances like color vision changes, not lens opacities. Warfarin and clonidine have no characteristic association with anterior subcapsular lens deposits.