Digoxin is known to cause which type of color defects?

• A. Blue/Yellow
• B. Red/Green
• C. Purple/Orange
• D. Brown/Gray

Answer: (A)

Digoxin can affect the retina and alter color perception, with the classic finding being xanthopsia—yellow-tinged vision. This yellowish disturbance is best described as a blue/yellow color defect, reflecting how digoxin toxicity changes color discrimination in the blue-yellow spectrum due to its effect on retinal cells. The other color vision defects (red/green, purple/orange, brown/gray) are not typical of digoxin toxicity, which is why blue/yellow is the correct association. This color change is a sign to review digoxin levels and assess for toxicity, alongside other symptoms like vision changes, nausea, or confusion.