Polysporin contains which two antibiotics?

• A. Bacitracin and Polymyxin B
• B. Bacitracin and Neomycin
• C. Polymyxin B and Neomycin
• D. Amoxicillin and Clavulanic acid

Answer: (A)

Polysporin is a topical antibiotic ointment that contains two antibiotics: bacitracin and polymyxin B. Bacitracin mainly targets gram-positive bacteria by inhibiting cell wall synthesis, while polymyxin B disrupts the outer membranes of gram-negative bacteria. Together, they provide broad coverage for common skin pathogens encountered with minor wounds, without including neomycin, which some people are allergic to. In contrast, products that contain neomycin (often sold as Neosporin) add a third antibiotic, and amoxicillin with clavulanic acid is an oral systemic antibiotic, not a topical agent.