Which fixed combination antibiotic-steroid product is used in ophthalmology to treat infections?

• A. Tobramycin + Dexamethasone
• B. Ciprofloxacin + Prednisolone
• C. Levofloxacin + Hydrocortisone
• D. Azithromycin + Dexamethasone

Answer: (A)

In ophthalmology, fixed combination products pair an antibiotic with a corticosteroid to address both infection and inflammation at the same time. The antibiotic targets the bacteria that cause ocular infections, while the corticosteroid reduces inflammatory symptoms like redness, swelling, and pain, which can help healing and comfort.

The best choice is the combination of tobramycin and dexamethasone. Tobramycin is an antibiotic effective against a broad range of gram-negative bacteria and some gram-positives commonly implicated in eye infections, and dexamethasone is a potent anti-inflammatory steroid that helps control the inflammatory response. Together, they provide both antimicrobial action and anti-inflammatory relief, which is why this fixed-dose product is a widely used option for treating ocular infections with inflammation.

Other combinations listed exist in various markets, but they are not as standard or widely recognized as a fixed-dose antibiotic-steroid option for eye infections. Remember, these drops should be used under medical supervision, and steroids should be avoided in viral or fungal keratitis or corneal ulcers until a clinician confirms the cause, due to potential complications like delayed healing or increased intraocular pressure with prolonged use.