Which influenza therapy inhibits both influenza A and influenza B?

• A. Zanamivir
• B. Oseltamivir
• C. Amantadine
• D. Rimantadine

Answer: (B)

Neuraminidase inhibitors prevent the release of newly formed influenza viruses from infected cells, limiting spread. This mechanism works against both influenza A and B because both types rely on neuraminidase to disseminate. Oseltamivir is an oral neuraminidase inhibitor that is effective against both influenza A and B and is used for treatment and post-exposure prophylaxis. The other major class here, the M2 ion-channel blockers, targets only influenza A and does not work against influenza B, which is why they’re not suitable when both types are a concern. Zanamivir also inhibits neuraminidase and covers both A and B, but the commonly used oral option highlighted here is oseltamivir.