Which is NOT a typical side effect associated with sulfa medications?

• A. Steven Johnson Syndrome
• B. Myopic Shift
• C. Hyperopic shift
• D. Pregnancy defects

Answer: (C)

Sulfa medications can cause a variety of adverse effects, including immune reactions, effects on pregnancy, and ocular changes. In the eye, a documented effect is a transient myopic shift caused by ciliochoroidal effusion, which pushes the lens forward and increases its refractive power. This makes the patient more near-sighted temporarily. Because the typical ocular change is myopia, a hyperopic (farsighted) shift is not a expected side effect. Additionally, severe hypersensitivity like Stevens-Johnson syndrome can occur, and sulfa drugs carry risks in pregnancy due to potential effects on the fetus. So, hyperopic shift is not a typical sulfa-related side effect.