Which of the following is NOT a side effect associated with Spironolactone?

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Multiple Choice

Which of the following is NOT a side effect associated with Spironolactone?

Explanation:
Spironolactone is a potassium-sparing diuretic that blocks aldosterone receptors in the distal nephron, which reduces potassium excretion and can raise potassium levels. Because of this mechanism, hyperkalemia is a known side effect. It also has antiandrogen effects that can lead to gynecomastia in men. Therefore, hypokalemia is not a typical side effect of spironolactone, while hyperkalemia, gynecomastia, and antiandrogen effects are.

Spironolactone is a potassium-sparing diuretic that blocks aldosterone receptors in the distal nephron, which reduces potassium excretion and can raise potassium levels. Because of this mechanism, hyperkalemia is a known side effect. It also has antiandrogen effects that can lead to gynecomastia in men. Therefore, hypokalemia is not a typical side effect of spironolactone, while hyperkalemia, gynecomastia, and antiandrogen effects are.

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