Which of the following is NOT one of the well known side effects of Penicillins?

• A. Type 1 hypersensitivity reaction
• B. Diarrhea
• C. Causes abortion of fetus in pregnant women
• D. Stevens-Johnson Syndrome

Answer: (C)

Penicillin adverse effects are typically allergic reactions, gastrointestinal upset, and, though rare, serious skin or mucous membrane reactions. A Type I hypersensitivity reaction is a classic example of an allergic response to penicillins, ranging from hives to anaphylaxis. Diarrhea is a commonGI side effect due to disruption of the gut microbiota. Stevens-Johnson syndrome is a rare but serious hypersensitivity reaction that has been reported with penicillins, though it is not common. Abortion of a fetus in pregnant women is not a recognized or well-known side effect of penicillins; in fact, penicillins are generally considered safe in pregnancy when indicated. Therefore, the statement about fetal abortion does not fit the typical adverse effect profile of penicillins.