Which of the following is NOT an ophthalmic indication for the use of a triamcinolone injection?

• A. Diabetic macular edema
• B. Irvine Gass Syndrome
• C. Wet AMD
• D. Intermediate uveitis

Answer: (C)

Intravitreal triamcinolone helps by reducing inflammation and stabilizing the blood-retinal barrier, which lowers macular edema in conditions with inflammatory or vascular leakage components. It’s commonly used for diabetic macular edema, Irvine-Gass syndrome (cystoid macular edema after cataract surgery), and intermediate uveitis. Wet age-related macular degeneration, on the other hand, is driven mainly by choroidal neovascularization and VEGF; anti-VEGF therapies are the standard treatment, and steroids have not shown the same level of efficacy. Therefore, wet AMD is not an indication for intravitreal triamcinolone.