Which of the following medications does NOT have anti-inflammatory properties?

• A. Ibuprofen
• B. Aspirin
• C. Fluticasone
• D. Acetaminophen

Answer: (D)

Antinflammatory effects come from lowering prostaglandin production in peripheral tissues. Ibuprofen and aspirin are NSAIDs that inhibit cyclooxygenase enzymes (COX-1 and COX-2), which reduces prostaglandins and thus inflammation, pain, and fever. Fluticasone is a corticosteroid; it suppresses inflammation through broad genomic effects that limit inflammatory mediator production and immune cell recruitment. Acetaminophen, while good for pain and fever, does not produce meaningful anti-inflammatory effects because its action is mainly central—comparing to peripheral inflammation, it has little impact there. So acetaminophen is the option without anti-inflammatory properties.